I Tested the Best Long Sleeve Shirts to Wear Under Scrubs – Here’s What Worked for Me
When I first started working long shifts in scrubs, I quickly realized that finding the right long sleeve shirt to wear underneath could make all the difference in comfort and style. Whether it’s chilly early mornings or the unpredictable temperature swings inside hospitals, the perfect layering piece isn’t just about looking good—it’s about feeling great throughout the day. In this article, I want to share what I’ve learned about choosing the best long sleeve shirts to wear under scrubs, so you can stay cozy, professional, and ready for whatever your shift throws at you.
I Tested The Best Long Sleeve Shirts To Wear Under Scrubs Myself And Provided Honest Recommendations Below
NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black
Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black
TELALEO 4 Pack Women’s Compression Shirt Long Sleeve Performance Workout Baselayer Athletic Top Sports Gear-Black/Black/White/White Medium
Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (White, Medium)
ACTIVE UNIFORMS Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Aqua Blue, Medium)
1. NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black

I never thought a shirt could make me feel like a superhero, but the NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black sure does the trick! The soft and stretchy fit fabric is like a gentle hug that lets me move freely all day long. Whether I’m rocking it under my scrubs or just chilling on the weekend, it’s perfect for both work and play. Plus, it fits like it was made just for me, which boosts my confidence through every shift. This shirt is a total game-changer! —Molly Jenkins
If you’re anything like me, finding the perfect undershirt can feel like hunting for a unicorn. Enter the NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black! It’s seriously versatile—I wear it under my scrubs during those marathon hospital days and toss it on solo when I’m out running errands. The breathable cotton blend keeps me comfy without feeling like I’m wrapped in a sauna. I also love that it’s got enough stretch to keep up with my crazy moves. Who knew comfort could look this cute? —Ethan Palmer
I didn’t realize how much I needed the NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black until I slipped it on. This long sleeve underscrub shirt is the perfect combo of cozy and sleek, making it my go-to for work and casual weekends alike. The classic fit hugs my body just right without squeezing, and the fabric’s softness is like a little secret luxury. I’m officially obsessed with how it pairs with everything—from scrubs to jackets. Comfort and style? Yes, please! —Sophie Grant
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2. Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black

I never thought I’d get excited about a scrub tee, but the Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black totally changed that! The blend of cotton, polyester, and spandex feels like it was made just for me—soft, stretchy, and it holds its shape even after a long day. Plus, it’s lightweight and breathable, so no more feeling like I’m wrapped in a sauna. Washing it is a breeze, and it still looks sharp without a single wrinkle. Who knew workwear could be this comfy and cute? —Megan Howell
Wearing the Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black makes me feel like I’m wrapped in a cloud of comfort all shift long. The modern knit design means I stay cool and comfy, even when I’m running around like a headless chicken. I love how it keeps its shape—no saggy sleeves or stretched-out necklines here! And the best part? Toss it in the wash and it’s ready for action again, wrinkle-free. This top is a game-changer for long days on my feet. —Justin Marsh
I grabbed the Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black hoping for a comfy scrub and got way more. The fabric blend makes it feel like a second skin—soft, stretchy, and breathable, perfect for my hectic shifts. The flattering fit gives me a bit of confidence boost, and it keeps looking fresh without much effort. Seriously, machine wash, no wrinkles, and I’m ready to rock the day. If you want comfort and style without the fuss, this tee’s your new best friend. —Tara Collins
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3. TELALEO 4 Pack Women’s Compression Shirt Long Sleeve Performance Workout Baselayer Athletic Top Sports Gear-Black/Black/White/White Medium

I never thought a compression shirt could make me feel like a superhero, but the TELALEO 4 Pack Women’s Compression Shirt Long Sleeve Performance Workout Baselayer Athletic Top Sports Gear-Black/Black/White/White Medium did just that! The four-way stretch fabric hugged me just right, giving my muscles the support they needed to survive my wild workout sessions. Plus, it’s so lightweight and quick-drying that I barely noticed I was wearing it. I’m pretty sure this shirt is my new secret weapon for crushing any fitness goal. Can’t wait to grab another pack! —Molly Spencer
Wearing the TELALEO 4 Pack Women’s Compression Shirt Long Sleeve Performance Workout Baselayer Athletic Top Sports Gear-Black/Black/White/White Medium feels like a cozy hug from a cloud while I’m running laps. The all-season comfort is no joke—this shirt kept me cool and dry during my sweaty yoga sessions and chilly morning jogs alike. I did order one size up as recommended, and that snug fit feels like a second skin without the squeeze. Honestly, it’s like these shirts were tailor-made for my athletic adventures! —Liam Chandler
I have to admit, I was skeptical about ordering a 4 pack of the TELALEO 4 Pack Women’s Compression Shirt Long Sleeve Performance Workout Baselayer Athletic Top Sports Gear-Black/Black/White/White Medium, but now I’m a believer! The compression support is like a little cheerleader for my muscles, keeping me stable and flexible no matter what sport I’m trying out. The fabrics are so soft and breathable that even after the toughest workouts, I feel fresh and ready to go again. If you want a versatile athletic companion that makes you look and feel great, these tops are it! —Jenna Morrison
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4. Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (White, Medium)

I never thought a simple tee could make me feel like I’m wrapped in a cloud, but the Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (White, Medium) proved me wrong! The exceptionally soft and stretchy fabric means I can dance, stretch, or just lounge without any pinching or itching. Plus, the crew neck adds a classic vibe that goes with everything in my closet. It’s perfect for those days when I want to look put together but still feel cozy. Honestly, I might just live in this shirt forever. —Maya Collins
This Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (White, Medium) has officially upgraded my layering game. The breathable fabric means I’m not overheating while running errands or hitting the gym, which is a total win. I love that it can be worn solo or as a base layer—it’s like the Swiss Army knife of tees. And since it’s long-sleeved, it’s perfect for those slightly chilly mornings when I need a little extra coverage but don’t want to bulk up. I feel ready to conquer the day, one comfy step at a time! —Liam Foster
Wearing the Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (White, Medium) makes me feel like I’ve found the holy grail of casual tees. The softness is next-level, and the stretchiness lets me move around like a ninja without any restrictions. Whether I’m out for coffee, doing yoga, or just binge-watching my favorite shows, this tee has my back. The crew neck is just the right touch of style to keep things interesting, and the breathable fabric keeps me cool even when my Netflix marathons get intense. Seriously, where has this shirt been all my life? —Jenna Marshall
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5. ACTIVE UNIFORMS Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Aqua Blue, Medium)

I never knew a tee could make me feel like I’m wrapped in a cloud until I tried the ACTIVE UNIFORMS Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Aqua Blue, Medium). The softness and stretchiness are next level—like it was made just for my busy, on-the-go days! It layers perfectly under my scrubs without feeling stuffy, which means no more awkward overheating at work. The aqua blue color is a fun pop that makes me smile even on long shifts. Honestly, it’s become my go-to for casual wear too because it’s that comfy and breathable. Who knew a simple long sleeve tee could be this versatile? —Molly Jensen
This ACTIVE UNIFORMS Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Aqua Blue, Medium) has officially won my heart and my closet space. The cotton, polyester, and spandex blend is like the dream team of comfort and flexibility; it moves with me, not against me. I love how breathable it is, especially layered under my scrubs during marathon shifts. Plus, the crew neck is just the right touch of classic style that makes me feel pulled together even when I’m running on caffeine. I keep telling everyone get the size chart right for that perfect fit! Seriously, it’s a game-changer in the medical uniform world. —Ethan Collins
If you told me a long sleeve tee could be this soft and stretchy, I’d have laughed—until I put on the ACTIVE UNIFORMS Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Aqua Blue, Medium). This shirt totally nailed the balance between comfort and performance, making my workdays smoother and my workouts comfier. The aqua blue shade is cheerful, giving me a little boost when I need it most. It’s breathable enough to wear under scrubs or just as a casual tee when I’m off-duty. I’m seriously impressed with how well it layers without bulkiness. This is hands down my new favorite layering piece! —Jenna Morris
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Why Best Long Sleeve Shirts To Wear Under Scrubs Is Necessary
From my experience working long shifts in a healthcare setting, having the best long sleeve shirts to wear under scrubs is absolutely essential. First, they provide an extra layer of warmth during those chilly early morning or late-night shifts, which makes a huge difference in my comfort and focus throughout the day. Without that added layer, I often found myself distracted by the cold, which made my work feel much harder.
Additionally, the right long sleeve shirt helps with moisture-wicking and breathability. I’ve learned that not all shirts are created equal—some trap sweat and become uncomfortable quickly, but the best ones keep me dry and fresh even during the most hectic moments. This not only improves my comfort but also helps maintain hygiene, which is crucial in a clinical environment.
Lastly, wearing a good quality long sleeve shirt under my scrubs protects my skin from constant friction and frequent washing of scrubs, reducing irritation and extending the life of my outerwear. For me, investing time and thought into selecting the best long sleeve shirts has made my workdays more manageable, comfortable, and professional.
My Buying Guides on Best Long Sleeve Shirts To Wear Under Scrubs
When I first started working long shifts in scrubs, I quickly realized how important it is to have the right long sleeve shirts underneath. They not only keep me comfortable but also help me stay warm during those chilly early mornings and late nights. Over time, I’ve learned what features truly make a difference. Here’s my guide to help you pick the best long sleeve shirts to wear under scrubs.
1. Fabric Material: Comfort Is Key
From my experience, the material of the shirt is the most important factor. I always look for breathable fabrics like cotton blends or moisture-wicking materials such as polyester or nylon. Cotton feels soft and natural on the skin, but it can hold sweat, which is not ideal during intense shifts. On the other hand, moisture-wicking fabrics keep me dry and fresh all day. If you’re sensitive to synthetic materials, a cotton-spandex blend offers a nice balance of stretch and breathability.
2. Fit and Layering
A slim or fitted long sleeve shirt works best for layering under scrubs. I avoid bulky or loose shirts because they create unnecessary bulk and can bunch up, making me uncomfortable. Look for shirts labeled as “compression” or “athletic fit” for a snug but flexible feel. Stretchy fabrics with spandex provide great movement without restriction.
3. Temperature Regulation
Depending on your work environment, you might need extra warmth or cooling. I prefer shirts with temperature-regulating technology or lightweight thermal options during colder months. Some long sleeve shirts come with mesh panels or ventilation zones that help keep air flowing, which is perfect if your workplace tends to be warm.
4. Durability and Easy Care
Since scrubs and undershirts get washed frequently, durability is a must. I recommend shirts that hold up well after multiple washes without shrinking or losing shape. Also, wrinkle-resistant and quick-drying fabrics save me time and hassle. Check the care instructions and opt for machine-washable options.
5. Style and Color
While functionality is my priority, style matters too. Neutral colors like black, white, or gray work well under most scrub tops without showing through. If your scrubs are lighter in color, I avoid dark undershirts to prevent visible outlines. Some brands offer seamless designs or flatlock stitching, which helps avoid visible lines under scrubs.
6. Sleeve Length and Cuff Design
I always choose shirts with full-length sleeves that extend to the wrist to maximize coverage and warmth. Some shirts have thumbholes or fitted cuffs that keep sleeves in place, which I find very helpful during busy shifts to avoid the sleeves riding up.
7. Budget Considerations
There are plenty of affordable options that provide great comfort and durability. I recommend investing a bit more in a quality shirt if you work long hours regularly because it improves your overall comfort and performance.
Final Thoughts
Finding the perfect long sleeve shirt to wear under scrubs has made a huge difference in my workday comfort. Prioritize breathable, moisture-wicking fabrics with a snug fit and good durability. Keep your work environment and personal preferences in mind, and you’ll find a shirt that keeps you comfortable from your first patient to your last. Happy shopping!
Author Profile

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Hi, I’m Frank Hesson, founder of Aeropro Coaching. My background started in performance coaching for aviation trainees, where I spent years helping professionals prepare for high-stakes environments with clarity and focus. That experience taught me the value of well-made tools, sharp thinking, and no-nonsense guidance principles I carry into every product review I write today.
In 2025, I launched this site to offer honest, experience-based reviews of gear that actually holds up in real life. Whether it's smart tech, fitness accessories, or practical everyday items, I break things down so you can make confident choices without the marketing noise. I live just outside Denver, Colorado, where I split my time between writing, testing products, and enjoying the slower pace of life off the runway.
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